Faculty of Computer Science

Dr. Christoph Bock

Research Group Workflow Systems and Technology
Währinger Straße 29
1090 Wien
christoph.bock(at)univie.ac.at
u:cris portal

Courses

Publications

Cell-type-specific requirement for TYK2 in murine immune cells under steady state and challenged conditions. / Karjalainen, Anzhelika; Witalisz-Siepracka, Agnieszka; Prchal-Murphy, Michaela et al.
In: Cellular and Molecular Life Sciences, Vol. 82, No. 1, 98, 12.2025.

Publications: Contribution to journal › Article › Peer Reviewed

doi.org/10.1007/s00018-025-05625-9

Multimodal learning enables chat-based exploration of single-cell data. / Schaefer, Moritz; Peneder, Peter; Malzl, Daniel et al.
In: Nature Biotechnology, 11.11.2025.

Publications: Contribution to journal › Article › Peer Reviewed

doi.org/10.1038/s41587-025-02857-9

Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation. / Traxler, Peter; Reichl, Stephan; Folkman, Lukas et al.
In: Cell Systems, Vol. 16, No. 8, 101346, 20.08.2025.

Publications: Contribution to journal › Article › Peer Reviewed

doi.org/10.1016/j.cels.2025.101346

PHLPP2 is a pseudophosphatase that lost activity in the metazoan ancestor. / Husremović, Tarik; Meier, Vanessa; Piëch, Lucas et al.
In: Proceedings of the National Academy of Sciences of the United States of America, Vol. 122, No. 14, e2417218122, 08.04.2025.

Publications: Contribution to journal › Article › Peer Reviewed

doi.org/10.1073/pnas.2417218122

JAK-STAT signaling maintains homeostasis in T cells and macrophages. / Fortelny, Nikolaus; Farlik, Matthias (Corresponding author); Fife, Victoria et al.
In: Nature Immunology, Vol. 25, No. 5, 05.2024, p. 847-859.

Publications: Contribution to journal › Article › Peer Reviewed

doi.org/10.1038/s41590-024-01804-1

Metabolic support by macrophages sustains colonic epithelial homeostasis. / Fritsch, Stephanie Deborah; Sukhbaatar, Nyamdelger; Gonzales, Karine et al.
In: Cell Metabolism, Vol. 35, No. 11, 07.11.2023, p. 1931-1943.e8.

Publications: Contribution to journal › Article › Peer Reviewed

doi.org/10.1016/j.cmet.2023.09.010

Systemic Inflammation and Normocytic Anemia in DOCK11 Deficiency. / Block, Jana; Rashkova, Christina; Castanon, Irinka et al.
In: The New England Journal of Medicine, Vol. 389, No. 6, 10.08.2023, p. 527 - 539.

Publications: Contribution to journal › Article › Peer Reviewed

doi.org/10.1056/NEJMoa2210054

Stress signaling boosts interferon-induced gene transcription in macrophages. / Boccuni, Laura; Podgorschek, Elke; Schmiedeberg, Moritz et al.
In: Science Signaling, Vol. 15, No. 764, eabq5389, 13.12.2022.

Publications: Contribution to journal › Article › Peer Reviewed

doi.org/10.1126/scisignal.abq5389

A toolbox for class I HDACs reveals isoform specific roles in gene regulation and protein acetylation. / Hess, Lena; Moos, Verena; Lauber, Arnel A et al.
In: PLoS Genetics, Vol. 18, No. 8, e1010376, 22.08.2022.

Publications: Contribution to journal › Article › Peer Reviewed

doi.org/10.1371/journal.pgen.1010376

Comprehensive Analysis of Nasal Polyps Reveals a More Pronounced Type 2 Transcriptomic Profile of Epithelial Cells and Mast Cells in Aspirin-Exacerbated Respiratory Disease. / Bangert, Christine; Villazala-Merino, Sergio; Fahrenberger, Martin et al.
In: Frontiers in Immunology, Vol. 13, 850494, 28.03.2022.

Publications: Contribution to journal › Article › Peer Reviewed

doi.org/10.3389/fimmu.2022.850494
1 - 10 out of 20

Projects

HDACs as Regulators of T-Cell-Mediated Immunity in Health and Disease

Hartl, M. (Project Lead), Ellmeier, W. (Project Coordinator), Bock, C. (Co-Lead), Bonelli, M. (Co-Lead), Boucheron, N. (Co-Lead), Gratz, I. (Co-Lead), Kuchler, K. (Co-Lead) & Seiser, C. (Co-Lead)

1/03/19 → 28/02/27

Project: Research funding